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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66a962a3f301ba7205f1682df36d0e01d2f839f842b30bfcee23741738398432' 
  AND token = 'YRHXm4nySVCfyS5qFVUx5he0MuaVLpMc7JnmrtUT1qY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}