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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19d8e0bc3d573185f40e4b69e59bafef5a4b15255338d5ee52b8ae3e47343005' 
  AND token = 'iqNuh1lwSxYcjabl32vVoLFXBgl8RWPmNZyAni1WAqA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}