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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a17db18e84e0bbbb9a5de0cd02fa01267cd9e0dad8498f5ed7701a309a22338' 
  AND token = 'VMMhmbGi2y4cjIQie33fILUZls7ljbXdFhvgwLfyiHA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}