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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e06514166286a6463316fbb7ee475a777a1761cefc61e05d516a5769f18e3954' 
  AND token = 'TlbhwW7Pc+SfUIFIVRUak5ovETk8kknxmK3rpdYkSfk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}