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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a78f42884a7d3147588f7c022eb660fcfb2c281d6ed2dfa2c996bccf8a2ece80' 
  AND token = '37HcSKn7zSJd3UyAJV8ll0j2nktrJfbhNyOBoG7447Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00063

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}