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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7de7385c918bb90da15e403405ee4873b462fcfec84486412040d06a7cfda014' 
  AND token = '+Tb+t6s8SCnuFwcnVH+Bh43GRa+rmxnwASt+G3EdHpo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}