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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d8f8beb1a9cc72ca71d41617f0dc0eceaf2e2e69981727bd13bcf431c46f6a5' 
  AND token = 'lgMnFEAIKrce+ymUs0q6z8nWw2sUY1RkyC0YpOwC3Lw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}