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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12f78af747cd447a7ee278d2f61497ae0518786d3b6d2082baeaddcd44dbd8ff' 
  AND token = 'PYkQbJf+dDMfHSwBe6C0KfZDmPaLL/FT37seWHrqod8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00073

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}