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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1049a382eb4b3c47ccf2c008040709676101440e88d2cb6508cec86db4e8813' 
  AND token = 'RzAMSmbTV0hsx4UyHknZEvYdQnj294NUb+SeH4C8EEs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}