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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7c2ec0f829cc5f676c4e9046e51c749f88fa1c492d64c1168644a10e5b4a5af' 
  AND token = 'eyCmg0s/A/MMfRbm4TZveTN2IPCd/GQOe9/QyM2gs/s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}