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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f53f1236f73d1c1b2514090cb1836d63ba3bb92be6f5dfe8f2ea2aabf3babd83' 
  AND token = 'Npa1xoN3+AgyHKhI2C/vsi4f1tQNX0up8HAn0i/fYdA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}