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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea793a699cc57108cda3d05dbf2625902ee2c99856516740c93c5aa0e7c59a2e' 
  AND token = 'ZVRCq8MKe2BroIJxBGs2iVQSID5yO1Kes6/PiyMYq+I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}