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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5befb079d1483c0fec18d956649517b477ea336616d8f2ce0be29c8f3a53d314' 
  AND token = 'NQk2DCq4j07OBqtTtLf2slnuvglqLl2i+Q32rly7sJQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}