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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d72cd1e0e4b10116baecc95216bff4fd7598f45c1faf9bc176dc2d1edffda41' 
  AND token = '4frS7fNpNsRhht2WEYIaDJEw+iuNoGTjmcQAymspkyg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}