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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e97ac32a477b87b2d1a3b8b53641008e49664a180722bad564162f9b2f431525' 
  AND token = 'uitU0bfTtDLxIx9KsGOejBZKCcDfnpIQ3hjZ6as2wzo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}