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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c01b69cd854b7e239b7f5bda0dd375f933b9ab2d3e41929aa5199b4f3fa441a' 
  AND token = '4D6mFfnFrWG6B8oC+s7IfIMJOBOjBdr364bXZ6wX+Ew=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}