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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28a04688ea58bbe2fe3d9482f585db405ff1d88b0f4844d3a6263e629e36a1dd' 
  AND token = 'BlRW1BYrz/HzQMVLJIr0VzyRS23GGr8h3OC1y+Vefyo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00060

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}