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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8bec2cf2856ec4a32365aba75752a587e68a5b9105019da0d74c887d38d2e563' 
  AND token = 'bq7X2TEVSS5vewP6iPzIL8dW6SIZ7BP1CKqubThcZPI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}