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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42e2796e00b20844d5816188d1bf72f88271856ac6c9847c00c513e276836b05' 
  AND token = 'HHREzXM7K2zk2n20nfqONdqfl63kkibxqIFIR4j9kcY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}