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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7fb55002c9313638e13fbd40fb6987baa5015c9d72a5f4c65fff8145d874a1a7' 
  AND token = 'RmQU2NoISu5PVAemTygDP+xjZPkXnAEgDdwa65TezcE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}