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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d7dff24060b3b8237b2e7e9eefe953441d67f0195426502bbda450f1899f5ce' 
  AND token = 'DHdDWdsFUKyz3B+vh4LlIeb7bF52EUvxtvxiMl1ismc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}