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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a889baecc36e58130906ef95e9364d18ed6b408061c2c484e219c71ec427ace' 
  AND token = '8QJfeY+N3OCBd/1nvo5Z8vex7w8JT7U9tlvnYFCQGcQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00068

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}