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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c50338f832ec4f23a9219287e1a4c730ff82d4ab789f3d9b2fa7b029b16066c1' 
  AND token = 'oYo7g60Dys9HT3+u16KY7Ipq/V3Pm8pwsH0gAWP/QCI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}