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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8ace276e8b5214f0283535c7d7c5a023a9649fe4deb261e5ab4ad4f08125499' 
  AND token = 'H23bBKSB+X8k9DJtN5EI091kr1lf18dtdsQrF2TQwJU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}