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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f14111f655c2f293bfd37aaae195c1c0ce657f1b8d405b2390720963a137a81d' 
  AND token = '4ZPD+/n18aKw3HuhVE0GPRG+1LhdJPXaRak7Snk3XUw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}