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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52510ce5351e6fe81a289367af4b3414b1739ec80d76f3f21a7b9df6043fb296' 
  AND token = 'sE1GUFDPGhfXPQiGTx6yjuaVWZZh/75n79rzSDVNhEM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}