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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1aeb2aa6c0451c047cb21ddf4404de14548491011224531e0401bc7236c440b0' 
  AND token = '1BuK2yZFGzpFrnj+Bxjp+GapKcv/qnW0VDj2sSt703c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}