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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '284d216b75283a0c85ff02a9c3463bffa5c15e1403a41e99a35833a828504f97' 
  AND token = 'wL2JfSd5tXsJQSpkK+AzyZet1PDCZ76D3kEvXYNVMzM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}