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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f4272785e7075ceebe3d5d7d8051b446bcca4bc8e1844875e439dc3de21db64' 
  AND token = 'iHt2Lyp+nZhyvu1jBRCSCy2gwYeXCmPiFHYhNpoFcas=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}