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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21c01c4e60f29ef45ea15c91fce8bc199601d86499c0e80a3f2a0a50ec238fba' 
  AND token = '3GrQweE0FUUcFGX8r6pBtZn/f27gnhK8SkJFEAaAobo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}