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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50d81bd8314ecff28681940f681c0c27048d2bfd11ad2a6fed22d988c3def0b3' 
  AND token = 'fgwuS7GpOo+7F2eNrz+AFQgC6PlvlsjSQFVzdnQm5zE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00063

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}