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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65527906c796d6ee6897bc5771063f4a32a017725816670cc7a37b49b7eb05a8' 
  AND token = 'o0/EkZMYg3rPd0YbHbh8Xe8dMMDGqBl1AZGmPRlMG6M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}