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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a35e6b7cea8cff664e802556b2555b788195c482b5e8dfd0ab24f7bfd948cb11' 
  AND token = 'nOAcLRN8Mr0SdQpx53HezPUpwCO/1B8HQJyNb0zbiZk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00074

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}