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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ce38a204592de2f9b4089b7830b8df713839bdb74352ee1cb38244760a7bf10' 
  AND token = 'eQBJ2T9TBKSZwCT0FgNx9YiMx5oP7fkLlli8lR6VqlU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}