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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '335683bf58df2896bd014e38a2fdb8444a664c16e393b2da758007f50fdbebcb' 
  AND token = 'ngmMZu2rTAOuDtZ3LzSJgf6VPH63XGWQuGB0fBbp+3o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}