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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f1950907ac4722cc0d229f2cce9e8ea43fa6581bd38da0ea6b0c59d399dfa10' 
  AND token = 'FqLPqGnx4RsAkEc8cmNH34ZwTMCeV2G8osI8Na8zmAQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}