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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '061151916ba4ee4d72a3018d8bd90a43285435f84578ab0e72c5aa575b294a41' 
  AND token = '6GJ5qqACYdv2yXhX0OkUwTmjUK1ykdD0sHgUwOmblGY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}