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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b508439911cc0d01a6d7b38ae5259ef8427f7b49fc0b6f093826880764c4fca' 
  AND token = 'MI+K4CHkotqyRRcMnQsCBiRzFNlHOAyf1XOzOslMxS0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}