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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cdb3b4a689baf1e7271ff4f250b7a253b3ef1be35570dac49c8a991d548a913' 
  AND token = 'E1Q8m1SBIWLfBKM5sWQeWyzUb2iy4ADfHv/A6+Jzpuk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}