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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '461b74a2b6ef3baabcb31eb38d2e61c7d4a27b5826d28617fee535ff88f57cba' 
  AND token = 's8Qk7qGXx9H3i+PeehzF4xFaEZi65mAyz+s0CPgrn0I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}