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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca21e707d6372065567e75adaf28e175fb011a8f95cdb8bed31be9de824e5a4d' 
  AND token = '/VjaqnM/KEDoMum3PjOGwflWCiouoFlglfl6RvcKfAg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}