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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b356d39fa7a36b90fc4fa921c4de0cbbe76a6cfc556378e183fee7faff104344' 
  AND token = 'fEjvObfSPmfFsQLmnfF3oscnVOCiHgxb6dfOV6eLqUc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}