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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d500207db8f239531d4f6a436fba231c7bcbded68a28b60f231fc4419fdfa59' 
  AND token = 'h1KTyyivCYtOrdNtJ0242Kyxn2RiYAnbBeY6YukmxnA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}