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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a59ddd62090f8752ca8f7b39cc2da86eb8d1f18d31ee1eadb43c673c6d3e7d0' 
  AND token = 'QI2ayjN1Pp1RDNbvCPq9LxcR4cFconaVWIigwGUFV9w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}