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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '100cade708f8efe122bca66fe9601ed742f1616d9750ef7530fb15130536f3e3' 
  AND token = 'ug6N39dO9z+iPKo+kCwqsJDo/ACD/IIPDe73v1sSs3Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}