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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78259db3c661616a92939454d35e8d42e680d7a589e15f3edf5e648137097ae6' 
  AND token = 'iMWs7EA84J13i89RVy1kQFjARf+We7v5hEx/q6ngDgk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}