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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60b885654ba118bd42a65287bf7496b34f0d5a5bbb94f7023039c77e98693037' 
  AND token = 'xcs27VnBVVZ2vNXnkDYsJ8FCiYRNybYHtOJZ2PpRFt4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}