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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00497606c5999a175981e4d62fb5c5919d49433da7f57037c4ae9a1862b50d32' 
  AND token = '0RUtFZNczzarVPjoJYyds+lsIppyZ4DmJCRp7uUmj1U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}