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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6aae1c8a88fb2faba0209b03f417da735117252a9e1c802745fc085fc1a1cb78' 
  AND token = '/bYrI01XMCGvhJ6XLTNuwc5N4e06qklJRBGwEbXWnjI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}