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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9524c126ec8c87902519203388f1b35a55a25935ae5a688f509e12e6c5b3d2d4' 
  AND token = 'DUs+PNXekApZtJeBKNYK1I5AQFJvHCssxvDFgVwoxeY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}